Liquid recombinant Arylsulfatase enzyme.
Store at 2-8°C for 12 months.

Product available on demand.
Lead time of 2 months for delivery.

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“The only pure recombinant arylsulfatase for steroid


Specifically designed for selective deconjugation of sulfo-conjugates while leaving 𝛃-glucuronide conjugates intact.


Finden ASPC-1



Product overview


ASPC™ is a recombinant arylsulfatase enzyme that efficiently deconjugates a wide range of sulfated moieties. Unlike most commercially available enzymes, which include glucuronidase enzymes, ASPC™ is a pure sulfatase that enables the hydrolysis of sulfates alone, with no other types of conjugations. 

Conjugation of xenobiotics represents an important biotransformation reaction in humans and animals. Hydrolysis of sulfo-conjugates is particularly relevant in steroid analysis, given that many steroids are converted into a mix of conjugates.

Because of its purity, ASPC™ avoids both conversions and the generation of interfering peaks typically produced by wild-type enzymes. Unlike wild-type versions, recombinant arylsulfatase can reach pure arylsulfatase activity. It is also significantly more stable, something that is difficult to achieve in wild-type enzymes.Learn about the ASPC benefitsSpecifications

Product Form: Solution, 10% (v/v) glycerol

Storage/Stability: 12 months at 2°C – 8°C

Temperature Range: 50 – 55°C

pH Range: 6.8 - 7.


Technical Datasheets

Technical DataSheet ASPC

Publications & Posters

Immobilized Enzymes on Magnetic Beads for Separate Mass Spectrometric Investigation of Human Phase II Metabolite Classes

Advanced Metabolomics Analysis Through Chemical Biology Tools for the Selective Investigation of Gut Microbiota-Derived Metabolites 

Comparison of two aryl sulfatases for targeted mass spectrometric analysis of microbiota derived metabolites

Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host

Development and characterization of an enzyme formulation for sulfatase and glucuronidase hydrolysis in a single step

Unique Chemical biology tools for advanced metabolomics analysis - exploring gut microbiota metabolism by Daniel Globisch

Enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites by Ioanna Tsiara


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