The use of β-glucuronidase and/or sulfatase plays an important role in the preparation of biological samples.
These enzymes cleave glucuronide and/or sulfate conjugates from the drug metabolite and convert it back into the free parent drug allowing for increased sensitivity and a simplified workflow.
Every test is critical, whether it's for TDM, forensic testing, workplace drug testing, anti-doping, or anything in between.
We believe your lab should have the best enzymes to ensure the best results.
Opiates & Opioids
Class of drugs that are used to reduce pain in natural, semi-synthetic and synthetic forms.
This includes THC-COOH, as well as other natural cannabinoids such as Cannabidiol (CBD).
Class of drugs that produces sedative, anti-anxiety, and anticonvulsant effects.
Buprenorphine is a partial opioid agonist and its active metabolite is norbuprenorphine.
These derivatives of cholesterol include β-glucuronides and/or sulfate conjugates.
Mass Spectrometry based proteomics has emerged as an extremely powerful tool that can be used for peptide fingerprinting, to identify thousands of proteins from complex samples, or to characterize its post-translational modifications.
Bottom-up and shotgun proteomics uses proteases to digest protein samples into peptides, while glycosidases are used for post-translational modifications analysis.
Meet the new sparkling science.
Provides a comprehensive overview of cellular processes, allowing a better understanding of diseases.
Discovery of drug targets, understand disease mechanisms and develop effective teatments to diseases.
Analysis of human tissues and fluids to detect and quantificate molecules that are related to a biological state or condition.